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Unusual Exaggerated Inflammatory Response in Fuchs Uveitis: A Case Report

 Department of Ophthalmology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India

Date of Submission02-May-2021
Date of Decision11-Jan-2022
Date of Acceptance18-Jan-2022
Date of Web Publication07-Nov-2022

Correspondence Address:
Samendra Karkhur,
Department of Ophthalmology, All India Institute of Medical Sciences, Bhopal 462020, Madhya Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/njo.njo_3_21


Objective: To report a case of Fuchs uveitis with an unusual exaggerated inflammatory response in the form of multifocal fibrin deposition. Case Report: Fuchs uveitis syndrome (FUS) has a characteristic clinical appearance but is frequently overlooked when heterochromia is subtle or absent. Specific atrophic changes in the iris, keratic precipitates, minimal cells and flare, the lack of posterior synechia, and the frequent presence of cataract and secondary glaucoma represent the clinical spectrum observed during the usual natural course of FUS. The occurrence of multifocal fibrin deposition on the entire iris surface in a young Indian male patient who presented with the clinical picture of Fuchs uveitis is reported. The finding of multifocal fibrin was unusual and thought to be an exaggerated inflammatory response in FUS. The patient was managed with topical corticosteroid therapy which resulted in complete resolution of fibrin. Regular follow-up was advised in view of the chronic nature of the disease and predisposition to complicated cataract and secondary glaucoma.

Keywords: Anterior uveitis, complicated cataract, Fuchs uveitis, iris atrophy, secondary glaucoma

How to cite this URL:
Karkhur S, Soni D, Patel S, Sharma R, Nyodu R, Sharma B. Unusual Exaggerated Inflammatory Response in Fuchs Uveitis: A Case Report. Niger J Ophthalmol [Epub ahead of print] [cited 2023 Jan 30]. Available from:



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