Year : 2019  |  Volume : 27  |  Issue : 1  |  Page : 8-11

Retinoblastoma in Onitsha, Nigeria

Guinness Eye Center, Onitsha, Nigeria

Correspondence Address:
Prof. Sebastian N N Nwosu
Guinness Eye Center, PMB 1534, Onitsha
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/njo.njo_20_18

Rights and Permissions

Objectives: This study aims to determine the incidence, pattern, and problems of management of retinoblastoma at the Guinness Eye Center, Onitsha, Nigeria. Materials and Methods: Case files of all patients with histology-proven retinoblastoma between October 2012 and September 2017 were reviewed. Information obtained included age, sex, disease duration, presenting features, and treatment. Results: There were 31 patients, 14 males (45.2%) and 17 females (54.8%), who had the disease in 38 eyes; age range was 5 months to 6 years; and median was 2.4 years. Disease duration was 3 weeks to 3 years and median was 8.8 months. Seven patients (22.6%) had bilateral disease, 11 (35.5%) had the disease only in the right eye, whereas 13 (41.9%) had the disease in the left eye; 32 (84.2%) eyes had no visual potential at presentation. The most common clinical features were leukocoria in 23 (60.5%) eyes and proptosis in 20 (52.6%). While all patients with advanced disease had enucleation or modified exenteration, only 15 (48.4%) accepted chemotherapy with two completing the full course and five not returning after the first course. Five (16.1%) had distant metastasis, namely, brain 2 (6.5%) and orbit, jaw, and skull 1 (3.2%) each. Conclusions: Retinoblastoma is seen at the Guinness Eye Center at the rate of about one case in 2 months. Most patients present late with proptosis and, in some cases, fungating necrotic tumor mass with distant metastases. There is a high default rate with treatment as only two patients completed the full course of chemotherapy.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded571    
    Comments [Add]    
    Cited by others 2    

Recommend this journal